Preimplantation Genetic Testing – Is It an Option for You?

Recently there have been name terminology changes. Preimplantation genetic screening (PGS) is now known as preimplantation genetic testing for aneuploidy (PGT-a) and preimplantation genetic diagnosis (PGD) is now known as preimplantation genetic testing for single gene defects (PGT-s). Both types of tests are used to identify genetic problems. PGT(a) or PGT(s) are performed before an embryo or embryos are transferred to the uterus.

What is preimplantation genetic testing for aneuploidy (PGT-a) and is it right for you?

Preimplantation genetic testing for aneuploidy (PGT-a) is a type of genetic screening used to confirm whether an embryo has the correct number of chromosomes; it does not test for a specific genetic disease. A chromosomal abnormality (aneuploidy) is the most common reason for implantation failure and miscarriage. Furthermore, aneuploidies increases as a woman’s eggs get older.

If you are having IVF treatment with your own eggs or if you have experienced recurrent miscarriages, your fertility specialist may recommend preimplantation genetic testing for aneuploidy (PGT-a) to increase your chances of transferring and implanting a healthy embryo.

Also, if you have had unsuccessful IVF cycles, you should consider preimplantation genetic testing for aneuploidy (PGT-a), since testing may help increase the success of your IVF cycle.

Many couples are choosing to use preimplantation genetic testing for aneuploidy (PGT-a) as a tool for family balancing as well. Preimplantation genetic testing for aneuploidy (PGT-a) for gender selection has become a common practice with IVF. 

What is preimplantation genetic testing for single gene defects (PGT-s) and is it right for you?

Preimplantation genetic testing for single gene defects (PGT-s) is a type of genetic screening that detects the presence of a mutated gene for a specific disease. This test is very important to both you and your partner, if there’s a family history of a genetic disease or if both of you are carriers for a genetic disease. Preimplantation genetic testing for single gene defects (PGT-s) can help ensure you are not passing along these genetic mutations to your child. Preimplantation genetic testing for single gene defects (PGT-s) may detect genetic disorders such as:

• Cystic fibrosis
• Down syndrome
• Hemophilia
• Huntington’s disease
• Muscular dystrophy
• Sickle cell anemia
• Smooth muscle atrophy
• Tay-Sachs disease

There are many other genetic diseases that can be detected with PGT(a) and PGT(s). Please schedule an appointment with Dr. Arnold to discuss.

If you are ready to grow your family with effective IVF treatment and are interested in preimplantation genetic testing at an accredited San Diego fertility center, please call California Center for Reproductive Medicine at 760-274-2000.